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PyrroloQuinoline Quinone (PQQ) is a vitamin-like compound found in plants and seems to offer a wide range of benefits to the brain and function of the body. PQQ is not currently considered a vitamin, however, it is most likely to be added to the list of essential nutrients in the future.
PQQ stimulates cellular function including cellular growth. It is also one of the most powerful antioxidants ever discovered, (some estimate up to 5,000 times more potent than typical antioxidants).
PQQ has been found in most plants, but especially in green plants such as spinach, parsley, kale, green peppers, kiwi fruit and papaya fruit.
There is no question in the scientific community that PQQ plays a critical role in human nutrition. In recent studies it was found that when PQQ is omitted from chemically defined diets in mammals it leads to growth impairment, compromised immune status, and abnormal reproductive function.
Yes, PQQ is a very important part of a healthy diet. It is estimated that the RDA will eventually be equivalent to the requirement of folate and biotin in our diets.
Early studies have revealed the following facts about PQQ:
- PQQ reverses cognitive impairment caused by chronic oxidative stress and improves memory performance.
- PQQ stimulates the production and release of nerve growth factor.
- PQQ protects against the self-oxidation of the DJ-1 gene, an early step in the onset of Parkinson’s disease.
- PQQ protects brain cells against oxidative damage in models of strokes.
- PQQ blocks the formation of inducible nitric oxide synthase (iNOS), a major source of reactive nitrogen species (RNS) that damage brain cells.
- PQQ protects against severe stroke in experimental animal models for stroke
- PQQ protects the brain against neurotoxicity induced by toxins, such as mercury, glutamate, and oxidopamine (a potent neurotoxin used by scientists to induce Parkinsonism in laboratory animals).
- PQQ prevents development of alpha-synuclein, a protein associated with Parkinson’s disease
- PQQ also protects nerve cells from the damaging effects of the beta-amyloid-protein linked with Alzheimer’s disease.
By way of its plant based nutrients, PQQ is in Promanatein. The exact levels of PyrroloQuinoline Quinone found in Promanatein is not yet known. 
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